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Published Sep 05, 19
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These are commonly observed in users who take more than 1500mg of CBD per day.It is important to make sure that users obtain the oil from trusted sources, which have been extracted using appropriate methods (without harsh chemicals) as cheap and fake products can cause toxicity and side effects.CBD oil might show certain interaction with commonly used drugs including certain anti-depressants, beta blockers, antibiotics, anesthetics, anti-anxiety, anti-epileptics/anti-seizure, some non-steroidal anti-inflammatory drugs (NSAIDs), etc.This is because CBD oil shows inhibition of the liver enzyme, cytochrome P450, and therefore the medications are not degraded as the usual rate resulting in increased concentration of the drugs in the serum of the users.The users should alter the dosage of those drugs accordingly to avoid any side effects.Pregnant and breastfeeding females should not use CBD oil unless recommended by the doctor, as its effects on the fetus/infants are not known.Users should also try to get an expert opinion on dose and drug interactions to avoid any unwanted effects associated with overdosing, etc.Recommendation from a doctor can also be helpful.

What Can CBD Oil Do to Reduce Joint Pain?What Can CBD Oil Do to Reduce Joint Pain?

among people. It can be caused due to many different reasons including injuries, systemic disorders, etc.CBD oil can provide relief from back pain owing to its analgesic, anti-inflammatory, anti-epileptic, anti-depressant, etc. property. Back pain caused due to lack of sleep can also be alleviated as CBD attenuates insomnia.Pure and high-quality CBD oil can be used by patients of any age group in order to alleviate back pain and experience overall comfort.There are several ways to consume CBD oil and it can be easily incorporated into one’s lifestyle.Recommendation from health care provider upon information like dose and drug interaction can help avoid side effects..

Recognized as the leading cause of disability worldwide, back pain is a common condition that can cause extreme discomfort – not to mention a few missed days of work or physical activity. Evidence suggests that 50% to 80% of adults will experience at least one episode of back pain at some point in their lives.

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As research into the benefits of cannabis continues, cannabidiol (CBD) has emerged as a potentially viable treatment for pain relief. CBD is a non-intoxicating cannabinoid found in the cannabis plant, second in abundance only to THC, and is widely perceived to help reduce pain. Therefore, it stands to reason that someone experiencing back pain might be wondering whether they can effectively use CBD oil for back pain.

When CBD interacts with the endocannabinoid system (ECS), which is an internal system that regulates our bodies, it enhances the signaling of anandamide, a pain-regulating compound found in the brain that is linked to feelings of well-being and happiness. By preventing the absorption of this molecule, CBD pushes excess quantities into the bloodstream, reducing pain throughout the body.

Photo by: Gina Coleman/Weedmaps CBD has also demonstrated the ability to reduce pain through the body's TRPV1 receptors, responsible for control functions such as inflammation and the awareness of pain. One study, published in the September 2015 edition of the journal Neurotoxicology, found that CBD also inhibits glutamate levels in the brain and spinal cord, which is associated with increased sensations of pain and transmission.

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In a 2012 study, also conducted on lab mice, researchers found that CBD targets alpha-3 glycine receptors to suppress chronic inflammatory and neuropathic pain associated with dysfunctional glycine receptors, an important target for pain processing by the spine, without causing any noticeable analgesic tolerance. There's no definitive answer yet, but a 2016 animal study published in European Journal of Pain found that topical application may be more effective than the sublingual method.

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There is evidence that CBD could reduce pain associated with osteoarthritis, a multifunctional joint disease that causes joint degeneration and inflammation. A 2017 study in the journal Pain found that local application of CBD reduced joint inflammation and prevented pain, suggesting that CBD would be an effective treatment for pain associated with arthritis.

CBD has also been examined as a treatment for other conditions that cause intense bouts with back pain. For instance, a 2014 study demonstrated that CBD reduced the severity of damage caused by disc degeneration in the vertebrae. After inflicting lab rates with a spinal injury, the research team injected them with various concentrations of CBD, and concluded that higher doses of CBD provided an anti-degenerative effect and “attenuated the effects of disc injury.” For some, chronic back pain may make it difficult to get a proper night of sleep, but a growing faction of research points to CBD as an effective sleep aid as well.

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